The Clinical Drug Ebselen Attenuates Inflammation and Promotes Microbiome Recovery in Mice after Antibiotic Treatment for CDI

Clostridium difficile infection (CDI) is an enteric bacterial disease that is increasing in prevalence worldwide. C. difficile capitalizes on gut inflammation and microbiome dysbiosis to establish infection, with symptoms ranging from watery diarrhea to toxic megacolon. We reported that the safe-in-...

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Pubblicato in:Cell Rep Med
Autori principali: Garland, Megan, Hryckowian, Andrew J., Tholen, Martina, Oresic Bender, Kristina, Van Treuren, William W., Loscher, Sebastian, Sonnenburg, Justin L., Bogyo, Matthew
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7263476/
https://ncbi.nlm.nih.gov/pubmed/32483557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xcrm.2020.100005
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