Exon skipping of TGFβRI affects signalling and ECM expression in hypertrophic scar-derived fibroblasts

BACKGROUND: In burn patients, wound healing is often accompanied by hypertrophic scar (HS) development, resulting in both functional and aesthetic problems. HSs are characterised by abundant presence of myofibroblasts that contribute to overproduction of extracellular matrix (ECM) that is regulated...

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Bibliografiske detaljer
Udgivet i:Scars Burn Heal
Main Authors: Raktoe, Rajiv S, Rietveld, Marion H, Out-Luiting, Jacoba J, Kruithof-de Julio, Marianna, van Zuijlen, Paul PM, van Doorn, Remco, Ghalbzouri, Abdoelwaheb El
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2020
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7263111/
https://ncbi.nlm.nih.gov/pubmed/32528734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2059513120908857
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