Exon skipping of TGFβRI affects signalling and ECM expression in hypertrophic scar-derived fibroblasts

BACKGROUND: In burn patients, wound healing is often accompanied by hypertrophic scar (HS) development, resulting in both functional and aesthetic problems. HSs are characterised by abundant presence of myofibroblasts that contribute to overproduction of extracellular matrix (ECM) that is regulated...

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Detalhes bibliográficos
Publicado no:Scars Burn Heal
Main Authors: Raktoe, Rajiv S, Rietveld, Marion H, Out-Luiting, Jacoba J, Kruithof-de Julio, Marianna, van Zuijlen, Paul PM, van Doorn, Remco, Ghalbzouri, Abdoelwaheb El
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7263111/
https://ncbi.nlm.nih.gov/pubmed/32528734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2059513120908857
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