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Copper(II) partially protects three histidine residues and the N‐terminus of amyloid‐β peptide from diethyl pyrocarbonate (DEPC) modification

Diethyl pyrocarbonate (DEPC) has been primarily used as a residue‐specific modifying agent to study the role of His residues in peptide/protein and enzyme function; however, its action is not specific, and several other residues can also be modified. In the current study, we monitored the reaction o...

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Vydáno v:FEBS Open Bio
Hlavní autoři: Friedemann, Merlin, Tõugu, Vello, Palumaa, Peep
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7262909/
https://ncbi.nlm.nih.gov/pubmed/32255544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12857
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