FTY720 Suppresses Liver Tumor Growth and Metastasis by Reducing Circulating Regulating T Cells and Enhancing the Anti-Tumor Effect of Rapamycin

BACKGROUND: In this study, we aimed to study the effect of FTY720 treatment in reducing circulating Tregs level and then suppressing liver tumor metastasis after hepatectomy and I/R injury in animal models. Furthermore, we also investigated the synergistic anti-tumor effect of FTY720 combined with r...

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Bibliografski detalji
Izdano u:Onco Targets Ther
Glavni autori: Li, Chang Xian, Yang, Xin Xiang, Wang, Hong Wei, Li, Xiang Cheng, Ng, Kevin Tak-Pan, Lo, Chung Mau, Man, Kwan
Format: Artigo
Jezik:Inglês
Izdano: Dove 2020
Teme:
Original Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7262652/
https://ncbi.nlm.nih.gov/pubmed/32547103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S234394
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