Tau PET imaging with (18)F-PI-2620 in Patients with Alzheimer Disease and Healthy Controls: A First-in-Humans Study

(18)F-PI-2620 is a PET tracer with high binding affinity for aggregated tau, a key pathologic feature of Alzheimer disease (AD) and other neurodegenerative disorders. Preclinically, (18)F-PI-2620 binds to both 3-repeat and 4-repeat tau isoforms. The purpose of this first-in-humans study was to evalu...

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Bibliografische gegevens
Gepubliceerd in:J Nucl Med
Hoofdauteurs: Mueller, Andre, Bullich, Santiago, Barret, Olivier, Madonia, Jennifer, Berndt, Mathias, Papin, Caroline, Perrotin, Audrey, Koglin, Norman, Kroth, Heiko, Pfeifer, Andrea, Tamagnan, Gilles, Seibyl, John P., Marek, Kenneth, De Santi, Susan, Dinkelborg, Ludger M., Stephens, Andrew W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society of Nuclear Medicine 2020
Onderwerpen:
Neurology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7262222/
https://ncbi.nlm.nih.gov/pubmed/31712323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.119.236224
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