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Saccharomyces cerevisiae ER membrane protein complex subunit 4 (EMC4) plays a crucial role in eIF2B-mediated translation regulation and survival under stress conditions
BACKGROUND: Eukaryotic initiation factor 2B (eIF2B) initiates and regulates translation initiation in eukaryotes. eIF2B gene mutations cause leukoencephalopathy called vanishing white matter disease (VWM) in humans and slow growth (Slg(−)) and general control derepression (Gcd(−)) phenotypes in Sacc...
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| Publicado no: | J Genet Eng Biotechnol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7261713/ https://ncbi.nlm.nih.gov/pubmed/32476094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s43141-020-00029-7 |
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