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Cellular phosphatidic acid sensor, α-synuclein N-terminal domain, detects endogenous phosphatidic acid in macrophagic phagosomes and neuronal growth cones

Phosphatidic acid (PA) is the simplest phospholipid and is involved in the regulation of various cellular events. Recently, we developed a new PA sensor, the N-terminal region of α-synuclein (α-Syn-N). However, whether α-Syn-N can sense physiologically produced, endogenous PA remains unclear. We fir...

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Bibliografiske detaljer
Udgivet i:Biochem Biophys Rep
Main Authors: Yamada, Haruka, Hoshino, Fumi, Lu, Qiang, Sakane, Fumio
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7261706/
https://ncbi.nlm.nih.gov/pubmed/32490215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2020.100769
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