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Cellular phosphatidic acid sensor, α-synuclein N-terminal domain, detects endogenous phosphatidic acid in macrophagic phagosomes and neuronal growth cones

Phosphatidic acid (PA) is the simplest phospholipid and is involved in the regulation of various cellular events. Recently, we developed a new PA sensor, the N-terminal region of α-synuclein (α-Syn-N). However, whether α-Syn-N can sense physiologically produced, endogenous PA remains unclear. We fir...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Rep
Main Authors: Yamada, Haruka, Hoshino, Fumi, Lu, Qiang, Sakane, Fumio
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7261706/
https://ncbi.nlm.nih.gov/pubmed/32490215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2020.100769
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