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Cellular phosphatidic acid sensor, α-synuclein N-terminal domain, detects endogenous phosphatidic acid in macrophagic phagosomes and neuronal growth cones

Phosphatidic acid (PA) is the simplest phospholipid and is involved in the regulation of various cellular events. Recently, we developed a new PA sensor, the N-terminal region of α-synuclein (α-Syn-N). However, whether α-Syn-N can sense physiologically produced, endogenous PA remains unclear. We fir...

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Dades bibliogràfiques
Publicat a:Biochem Biophys Rep
Autors principals: Yamada, Haruka, Hoshino, Fumi, Lu, Qiang, Sakane, Fumio
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7261706/
https://ncbi.nlm.nih.gov/pubmed/32490215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2020.100769
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