Notch-mediated lateral induction is necessary to maintain vestibular prosensory identity during inner ear development

The five vestibular organs of the inner ear derive from patches of prosensory cells that express the transcription factor SOX2 and the Notch ligand JAG1. Previous work suggests that JAG1-mediated Notch signaling is both necessary and sufficient for prosensory formation and that the separation of dev...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Dev Biol
Hauptverfasser: Brown, Rogers M., Nelson, Joel C., Zhang, Hongyuan, Kiernan, Amy E., Groves, Andrew K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7261482/
https://ncbi.nlm.nih.gov/pubmed/32147304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2020.02.015
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge