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Notch-mediated lateral induction is necessary to maintain vestibular prosensory identity during inner ear development

The five vestibular organs of the inner ear derive from patches of prosensory cells that express the transcription factor SOX2 and the Notch ligand JAG1. Previous work suggests that JAG1-mediated Notch signaling is both necessary and sufficient for prosensory formation and that the separation of dev...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Dev Biol
Egile Nagusiak: Brown, Rogers M., Nelson, Joel C., Zhang, Hongyuan, Kiernan, Amy E., Groves, Andrew K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7261482/
https://ncbi.nlm.nih.gov/pubmed/32147304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2020.02.015
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