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Notch-mediated lateral induction is necessary to maintain vestibular prosensory identity during inner ear development
The five vestibular organs of the inner ear derive from patches of prosensory cells that express the transcription factor SOX2 and the Notch ligand JAG1. Previous work suggests that JAG1-mediated Notch signaling is both necessary and sufficient for prosensory formation and that the separation of dev...
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| Vydáno v: | Dev Biol |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7261482/ https://ncbi.nlm.nih.gov/pubmed/32147304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2020.02.015 |
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