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Non-viral nanoparticles for CRISPR-based genome editing: is it just a simple adaption of what have been developed for nucleic acid delivery?
Genome-editing technologies hold tremendous potential for treating genetic diseases. However, the efficient and safe delivery of genome-editing elements to the location of interest, and the achievement of specific targeted gene correction without off-target side effect remains a big challenge. In th...
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| Gepubliceerd in: | Biomacromolecules |
|---|---|
| Hoofdauteurs: | , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7261392/ https://ncbi.nlm.nih.gov/pubmed/31342740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biomac.9b00783 |
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