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Non-viral nanoparticles for CRISPR-based genome editing: is it just a simple adaption of what have been developed for nucleic acid delivery?

Genome-editing technologies hold tremendous potential for treating genetic diseases. However, the efficient and safe delivery of genome-editing elements to the location of interest, and the achievement of specific targeted gene correction without off-target side effect remains a big challenge. In th...

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Dades bibliogràfiques
Publicat a:Biomacromolecules
Autors principals: Qiu, Min, Glass, Zachary, Xu, Qiaobing
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7261392/
https://ncbi.nlm.nih.gov/pubmed/31342740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biomac.9b00783
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