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Experimental and Computational Studies on Regiodivergent Chiral Phosphoric Acid Catalyzed Cycloisomerization of Mupirocin Methyl Ester

This article presents a new strategy for achieving regiocontrol over the endo versus exo modes of cycloisomerizations of epoxide-containing alcohols, which leads to the formation of five- or six-membered cyclic ethers. Unlike traditional methods relying on achiral reagents or enzymes, this approach...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Chemistry
Egile Nagusiak: Wang, Sibin, Arguelles, Alonso J., Tay, Jia-Hui, Hotta, Miyuki, Zimmerman, Paul M., Nagorny, Pavel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7261366/
https://ncbi.nlm.nih.gov/pubmed/31905253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201905222
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