CD4(+) T Cells Cross-Reactive with Dengue and Zika Viruses Protect against Zika Virus Infection

The underlying mechanisms by which prior immunity to dengue virus (DENV) affords cross-protection against the related flavivirus Zika virus (ZIKV) are poorly understood. Here, we examine the ability of DENV/ZIKV-cross-reactive CD4(+) T cells to protect against versus exacerbate ZIKV infection by usi...

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Veröffentlicht in:Cell Rep
Hauptverfasser: Wen, Jinsheng, Wang, Ying-Ting, Valentine, Kristen M., Alves, Rúbens Prince dos Santos, Xu, Zhigang, Regla-Nava, Jose Angel, Ngono, Annie Elong, Young, Matthew P., Ferreira, Luís C.S., Shresta, Sujan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7261136/
https://ncbi.nlm.nih.gov/pubmed/32348763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107566
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