Cross-reactive Dengue virus-specific CD8(+) T cells protect against Zika virus during pregnancy

As Zika virus (ZIKV) emerges into Dengue virus (DENV)-endemic areas, cases of ZIKV infection in DENV-immune pregnant women may rise. Here we show that prior DENV immunity affects maternal and fetal ZIKV infection in pregnancy using sequential DENV and ZIKV infection models. Fetuses in ZIKV-infected...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Regla-Nava, Jose Angel, Elong Ngono, Annie, Viramontes, Karla M., Huynh, Anh-Thy, Wang, Ying-Ting, Nguyen, Anh-Viet T., Salgado, Rebecca, Mamidi, Anila, Kim, Kenneth, Diamond, Michael S., Shresta, Sujan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072705/
https://ncbi.nlm.nih.gov/pubmed/30072692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05458-0
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