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Steric occlusion regulates proximal interactions of acyl carrier protein domain in fungal fatty acid synthase
The acyl carrier protein (ACP) domain shuttles substrates and reaction intermediates in type I fungal fatty acid synthases via transient protein-protein interactions. Here, using electron cryo-microscopy (cryoEM), we report the structure of a fungal FAS stalled at the dehydration reaction, which pre...
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| Publicado no: | Commun Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7260205/ https://ncbi.nlm.nih.gov/pubmed/32471977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-0997-y |
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