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Exploring the Reaction Mechanism of HIV RT with a Nucleotide Substrate

Enzymatic reactions consist of several steps, (i) a weak binding event of the substrate to the enzyme, (ii) an induced fit or a protein conformational transition upon ligand binding, (iii) the chemical reaction, and (iv) the release of the product. Here we focus on step (iii) of the reaction of a DN...

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Detalhes bibliográficos
Publicado no:J Phys Chem B
Main Authors: Wang, Hao, Huang, Nathan, Dangerfield, Tyler, Johnson, Kenneth A., Gao, Jiali, Elber, Ron
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7260111/
https://ncbi.nlm.nih.gov/pubmed/32364738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.0c02632
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