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Insulin-stimulated lipogenesis gets an epigenetic makeover

Hepatic de novo lipogenesis is a major contributor to nonalcoholic fatty liver disease (NAFLD). In this issue of the JCI, Liu and Lin et al. identified Slug as an epigenetic regulator of lipogenesis. Their findings suggest that Slug is stabilized by insulin signaling, and that it promotes lipogenesi...

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Foilsithe in:J Clin Invest
Main Authors: Manuel, Clarence R., Haeusler, Rebecca A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Clinical Investigation 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7260037/
https://ncbi.nlm.nih.gov/pubmed/32364539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI137050
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