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Insulin-stimulated lipogenesis gets an epigenetic makeover

Hepatic de novo lipogenesis is a major contributor to nonalcoholic fatty liver disease (NAFLD). In this issue of the JCI, Liu and Lin et al. identified Slug as an epigenetic regulator of lipogenesis. Their findings suggest that Slug is stabilized by insulin signaling, and that it promotes lipogenesi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Manuel, Clarence R., Haeusler, Rebecca A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7260037/
https://ncbi.nlm.nih.gov/pubmed/32364539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI137050
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