Tissue-resident T cell–derived cytokines eliminate herpes simplex virus-2–infected cells

The mechanisms underlying rapid elimination of herpes simplex virus-2 (HSV-2) in the human genital tract despite low CD8(+) and CD4(+) tissue-resident T cell (Trm cell) density are unknown. We analyzed shedding episodes during chronic HSV-2 infection; viral clearance always predominated within 24 ho...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Roychoudhury, Pavitra, Swan, David A., Duke, Elizabeth, Corey, Lawrence, Zhu, Jia, Davé, Veronica, Spuhler, Laura Richert, Lund, Jennifer M., Prlic, Martin, Schiffer, Joshua T.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7260013/
https://ncbi.nlm.nih.gov/pubmed/32125285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI132583
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