Post-sepsis immunosuppression depends on NKT cell regulation of mTOR/IFN-γ in NK cells

As treatment of the early, inflammatory phase of sepsis improves, post-sepsis immunosuppression and secondary infection have increased in importance. How early inflammation drives immunosuppression remains unclear. Although IFN-γ typically helps microbial clearance, we found that increased plasma IF...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Kim, Edy Y., Ner-Gaon, Hadas, Varon, Jack, Cullen, Aidan M., Guo, Jingyu, Choi, Jiyoung, Barragan-Bradford, Diana, Higuera, Angelica, Pinilla-Vera, Mayra, Short, Samuel A.P., Arciniegas-Rubio, Antonio, Tamura, Tomoyoshi, Leaf, David E., Baron, Rebecca M., Shay, Tal, Brenner, Michael B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7260006/
https://ncbi.nlm.nih.gov/pubmed/32154791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI128075
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados