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Rapid exposure of macrophages to drugs resolves four classes of effects on the leading edge sensory pseudopod: Non-perturbing, adaptive, disruptive, and activating

Leukocyte migration is controlled by a membrane-based chemosensory pathway on the leading edge pseudopod that guides cell movement up attractant gradients during the innate immune and inflammatory responses. This study employed single cell and population imaging to investigate drug-induced perturbat...

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Pubblicato in:PLoS One
Autori principali: Buckles, Thomas C., Ziemba, Brian P., Djukovic, Danijel, Falke, Joseph J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259666/
https://ncbi.nlm.nih.gov/pubmed/32469878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0233012
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