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Ca(2+) influx is an essential component of the positive-feedback loop that maintains leading-edge structure and activity in macrophages
In migrating eukaryotic cells, phosphatidylinositol 3-kinase (PI3K), filamentous actin (F-actin), and monomeric Rho GTPases are key components of a complex positive-feedback system that maintains and amplifies a phosphatidylinositol-3,4,5-trisphosphate signal at the leading edge of the cell. This li...
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| Huvudupphovsmän: | , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
National Academy of Sciences
2007
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2042181/ https://ncbi.nlm.nih.gov/pubmed/17911247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707719104 |
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