Amyloid β induces interneuron-specific changes in the hippocampus of APP(NL-F) mice

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by cognitive decline and amyloid-beta (Aβ) depositions generated by the proteolysis of amyloid precursor protein (APP) in the brain. In APP(NL-F) mice, APP gene was humanized and contains two familial AD mutations, and APP–unlike...

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Publicado en:PLoS One
Main Authors: Sos, Katalin E., Mayer, Márton I., Takács, Virág T., Major, Abel, Bardóczi, Zsuzsanna, Beres, Barnabas M., Szeles, Tamás, Saito, Takashi, Saido, Takaomi C., Mody, István, Freund, Tamás F., Nyiri, Gábor
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2020
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259556/
https://ncbi.nlm.nih.gov/pubmed/32469963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0233700
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