Maternal erythrocyte ENT1–mediated AMPK activation counteracts placental hypoxia and supports fetal growth

Insufficient O(2) supply is frequently associated with fetal growth restriction (FGR), a leading cause of perinatal mortality and morbidity. Although the erythrocyte is the most abundant and only cell type to deliver O(2) in our body, its function and regulatory mechanism in FGR remain unknown. Here...

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Vydáno v:JCI Insight
Hlavní autoři: Sayama, Seisuke, Song, Anren, Brown, Benjamin C., Couturier, Jacob, Cai, Xiaoli, Xu, Ping, Chen, Changhan, Zheng, Yangxi, Iriyama, Takayuki, Sibai, Baha, Longo, Monica, Kellems, Rodney E., D’Alessandro, Angelo, Xia, Yang
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259528/
https://ncbi.nlm.nih.gov/pubmed/32434995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.130205
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