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Gpr44 Mediates the Selenium-Dependent Anti-Leukemic Effect in Acute Myeloid Leukemia

OBJECTIVES: The relapse of acute myeloid leukemia (AML) remains a significant concern due to persistent leukemia stem cells (LSCs) that are not targeted by existing therapies. LSCs show sensitivity to endogenous cyclopentenone prostaglandin J (CyPG) metabolites that are increased by dietary trace el...

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Detalhes bibliográficos
Publicado no:Curr Dev Nutr
Main Authors: Qian, Fenghua, Tukaramrao, Diwakar, Zhou, Jiayan, Palmiero, Nicole, Arner, Brooke, Hall, Molly, Paulson, Robert, Prabhu, K Sandeep
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259215/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cdn/nzaa067_062
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