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The high expression of MTH1 and NUDT5 predict a poor survival and are associated with malignancy of esophageal squamous cell carcinoma

BACKGROUND: MTH1 and NUDT5 effectively degrade nucleotides containing 8-oxoguanine. MTH1 and NUDT5 have been linked to the malignancy of multiple cancers. However, their functions in tumor growth and metastasis in esophageal squamous carcinoma (ESCC) remain obscure. Our present study aims to explore...

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Bibliografske podrobnosti
izdano v:PeerJ
Main Authors: Wang, Jing-Jing, Liu, Teng-Hui, Li, Jin, Li, Dan-Ni, Tian, Xin-Yuan, Ouyang, Qiu-Geng, Cai, Jian-Ping
Format: Artigo
Jezik:Inglês
Izdano: PeerJ Inc. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7258951/
https://ncbi.nlm.nih.gov/pubmed/32518727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.9195
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