The high expression of MTH1 and NUDT5 predict a poor survival and are associated with malignancy of esophageal squamous cell carcinoma

BACKGROUND: MTH1 and NUDT5 effectively degrade nucleotides containing 8-oxoguanine. MTH1 and NUDT5 have been linked to the malignancy of multiple cancers. However, their functions in tumor growth and metastasis in esophageal squamous carcinoma (ESCC) remain obscure. Our present study aims to explore...

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Veröffentlicht in:PeerJ
Hauptverfasser: Wang, Jing-Jing, Liu, Teng-Hui, Li, Jin, Li, Dan-Ni, Tian, Xin-Yuan, Ouyang, Qiu-Geng, Cai, Jian-Ping
Format: Artigo
Sprache:Inglês
Veröffentlicht: PeerJ Inc. 2020
Schlagworte:
Bioinformatics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7258951/
https://ncbi.nlm.nih.gov/pubmed/32518727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.9195
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