Free Choline, but Not Phosphatidylcholine, Elevates Circulating Trimethylamine-N-oxide and This Response Is Modified by the Gut Microbiota Composition in Healthy Men

OBJECTIVES: Trimethylamine-N-oxide (TMAO), a choline-derived gut microbiota-dependent metabolite, is a newly recognized risk marker for cardiovascular disease. However, the contributions of different forms of choline and gut microbiota composition on TMAO production are largely unknown. The objectiv...

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Detalhes bibliográficos
Publicado no:Curr Dev Nutr
Main Authors: Cho, Clara, Aardema, Niklas D J, Bunnell, Madison L, Larson, Deanna P, Aguilar, Sheryl S, Bergeson, Janet R, Malysheva, Olga V, Caudill, Marie A, Lefevre, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Dietary Bioactive Components
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7258772/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cdn/nzaa045_012
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