Dietary β-Hydroxy-β-Methylbutyrate Supplementation Promotes PDAC Response to Gemcitabine and Immunotherapy Response in Obese Mice

OBJECTIVES: Late diagnosis, aggressive underlying biology, and limited treatment options contribute towards the exceptionally poor survival of pancreatic ductal adenocarcinoma (PDAC). Obesity promotes both incidence and progression of PDAC via chronic systemic inflammation, generation of an immunosu...

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Bibliografische gegevens
Gepubliceerd in:Curr Dev Nutr
Hoofdauteurs: Coleman, Michael, Liu, Kristyn, Tang, Xiaohu, Lashinger, Laura, Cui, Zhengrong, Hursting, Stephen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2020
Onderwerpen:
Diet and Cancer
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7257762/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cdn/nzaa044_012
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