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The HDAC Inhibitor Emodin Blocks Hypertension-Induced Cardiac Hypertrophy: A Mediating Role for the Gut?

OBJECTIVES: Evidence suggests that food bioactives impact the epigenome to prevent pathological cardiac hypertrophy. Recently, we showed that emodin, an anthraquinone, attenuated pathological cardiac hypertrophy and histone deacetylase (HDAC) activity. However, we only examined the cardioprotective...

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Detalhes bibliográficos
Publicado no:Curr Dev Nutr
Main Authors: Evans, Levi, Ferguson, Brad
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7257268/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cdn/nzaa045_029
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