TREM2 activation attenuates neuroinflammation and neuronal apoptosis via PI3K/Akt pathway after intracerebral hemorrhage in mice

BACKGROUND: Neuroinflammation is an important host defense response to secondary brain injury after intracerebral hemorrhage (ICH). Triggering receptor expressed on myeloid cells 2 (TREM2) confers strong neuroprotective effects by attenuating neuroinflammation in experimental ischemic stroke. Recent...

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Bibliografiske detaljer
Udgivet i:J Neuroinflammation
Main Authors: Chen, Shengpan, Peng, Jianhua, Sherchan, Prativa, Ma, Yongjie, Xiang, Sishi, Yan, Feng, Zhao, Hao, Jiang, Yong, Wang, Ning, Zhang, John H., Zhang, Hongqi
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7257134/
https://ncbi.nlm.nih.gov/pubmed/32466767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-020-01853-x
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