In-silico homology assisted identification of inhibitor of RNA binding against 2019-nCoV N-protein (N terminal domain)

The N terminal domain (NTD) of Nucleocapsid protein (N protein) of coronavirus (CoV) binds to the viral (+) sense RNA and results in CoV ribonucleoprotien (CoV RNP) complex, essential for the virus replication. In this study, the RNA-binding N terminal domain (NTD) of the N protein was targeted for...

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Détails bibliographiques
Publié dans:J Biomol Struct Dyn
Auteurs principaux: Sarma, Phulen, Shekhar, Nishant, Prajapat, Manisha, Avti, Pramod, Kaur, Hardeep, Kumar, Subodh, Singh, Sanjay, Kumar, Harish, Prakash, Ajay, Dhibar, Deba Prasad, Medhi, Bikash
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2020
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7256351/
https://ncbi.nlm.nih.gov/pubmed/32266867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/07391102.2020.1753580
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