Structural and conformational analysis of SARS CoV 2 N-CTD revealing monomeric and dimeric active sites during the RNA-binding and stabilization: Insights towards potential inhibitors for N-CTD

The advent of SARS-CoV-2 has become a universal health issue with no appropriate cure available to date. The coronavirus nucleocapsid (N) protein combines viral genomic RNA into a ribonucleoprotein and protects the viral genome from the host's nucleases. Structurally, the N protein comprises tw...

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Detalhes bibliográficos
Publicado no:Comput Biol Med
Main Authors: Chauhan, Arushi, Avti, Pramod, Shekhar, Nishant, Prajapat, Manisha, Sarma, Phulen, Bhattacharyya, Anusuya, Kumar, Subodh, Kaur, Hardeep, Prakash, Ajay, Medhi, Bikash
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Ltd. 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8123409/
https://ncbi.nlm.nih.gov/pubmed/34022485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.compbiomed.2021.104495
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