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Structure-based modeling of SARS-CoV-2 peptide/HLA-A02 antigens

As a first step toward the development of diagnostic and therapeutic tools to fight the Coronavirus disease (COVID-19), it is important to characterize CD8+ T cell epitopes in the SARS-CoV-2 peptidome that can trigger adaptive immune responses. Here, we use RosettaMHC, a comparative modeling approac...

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Bibliographic Details
Published in:bioRxiv
Main Authors: Nerli, Santrupti, Sgourakis, Nikolaos G.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7255794/
https://ncbi.nlm.nih.gov/pubmed/32511353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.03.23.004176
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