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Structural and functional characterization of the dominant negative P‐loop lysine mutation in the dynamin superfamily protein Vps1
Dynamin‐superfamily proteins (DSPs) are large self‐assembling mechanochemical GTPases that harness GTP hydrolysis to drive membrane remodeling events needed for many cellular processes. Mutation to alanine of a fully conserved lysine within the P‐loop of the DSP GTPase domain results in abrogation o...
Shranjeno v:
| izdano v: | Protein Sci |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
John Wiley & Sons, Inc.
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7255512/ https://ncbi.nlm.nih.gov/pubmed/31981262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3830 |
| Oznake: |
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