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Ivy1 is a negative regulator of Gtr-dependent TORC1 activation
The highly conserved TORC1 complex controls cell growth in response to nutrients, especially amino acids. The EGO complex activates TORC1 in response to glutamine and leucine. Here, we demonstrate that the I-BAR domain-containing protein Ivy1 colocalizes with Gtr1 and Gtr2, a heterodimer of small GT...
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| Foilsithe in: | J Cell Sci |
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| Main Authors: | , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
The Company of Biologists Ltd
2018
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6140320/ https://ncbi.nlm.nih.gov/pubmed/30097557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.218305 |
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