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The Gαq/ Phospholipase Cβ signaling system represses tau aggregation
Alzheimer’s disease is typified by calcium dysfunction and neurofibrillary tangles of tau aggregates along with mitotic proteins. Using PC12 cells as a model system, we determined whether the Gαq/PLCβ/calcium signaling pathway impacts the manifestation of Alzheimer’s disease. Down-regulating PLCβ si...
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| 出版年: | Cell Signal |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7255494/ https://ncbi.nlm.nih.gov/pubmed/32247043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2020.109620 |
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