NLRP3 Inflammasome and Glia Maturation Factor Coordinately Regulate Neuroinflammation and Neuronal Loss in MPTP Mouse Model of Parkinson’s Disease

Neuroinflammation plays an active role in the pathogenesis of several neurodegenerative diseases, including Parkinson’s disease (PD). Earlier studies from this laboratory showed that glia maturation factor (GMF), a proinflammatory mediator; is up-regulated in the brain in neurodegenerative diseases...

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發表在:Int Immunopharmacol
Main Authors: Javed, Hayate, Thangavel, Ramasamy, Selvakumar, Govindhasamy Pushpavathi, Dubova, Iuliia, Schwartz, Noah, Ahmed, Mohammad Ejaz, Zaheer, Smita, Kempuraj, Duraisamy, Iyer, Shankar, Zaheer, Asgar, Khan, Mohammad Moshahid
格式: Artigo
語言:Inglês
出版: 2020
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7255416/
https://ncbi.nlm.nih.gov/pubmed/32259702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.intimp.2020.106441
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