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Reprogramming axial level identity to rescue neural crest-related congenital heart defects
The cardiac neural crest arises in the hindbrain, then migrates to the heart and contributes to critical structures, including the outflow tract septum. Chick cardiac crest ablation results in failure of this septation, phenocopying the human heart defect Persistent Truncus Arteriosus (PTA), which t...
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| Publicado no: | Dev Cell |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7255058/ https://ncbi.nlm.nih.gov/pubmed/32369742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2020.04.005 |
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