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Reprogramming axial level identity to rescue neural crest-related congenital heart defects

The cardiac neural crest arises in the hindbrain, then migrates to the heart and contributes to critical structures, including the outflow tract septum. Chick cardiac crest ablation results in failure of this septation, phenocopying the human heart defect Persistent Truncus Arteriosus (PTA), which t...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Dev Cell
Päätekijät: Gandhi, Shashank, Ezin, Max, Bronner, Marianne E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7255058/
https://ncbi.nlm.nih.gov/pubmed/32369742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2020.04.005
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