Comparative study of preclinical mouse models of high-grade glioma for nanomedicine research: the importance of reproducing blood-brain barrier heterogeneity

The clinical translation of new nanoparticle-based therapies for high-grade glioma (HGG) remains extremely poor. This has partly been due to the lack of suitable preclinical mouse models capable of replicating the complex characteristics of recurrent HGG (rHGG), namely the heterogeneous structural a...

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Библиографические подробности
Опубликовано в: :Theranostics
Главные авторы: Brighi, Caterina, Reid, Lee, Genovesi, Laura A, Kojic, Marija, Millar, Amanda, Bruce, Zara, White, Alison L, Day, Bryan W, Rose, Stephen, Whittaker, Andrew K, Puttick, Simon
Формат: Artigo
Язык:Inglês
Опубликовано: Ivyspring International Publisher 2020
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7255036/
https://ncbi.nlm.nih.gov/pubmed/32483457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.46468
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