MGAT3-mediated glycosylation of tetraspanin CD82 at asparagine 157 suppresses ovarian cancer metastasis by inhibiting the integrin signaling pathway

Background: Tetraspanins constitute a family of transmembrane spanning proteins that function mainly by organizing the plasma membrane into micro-domains. CD82, a member of tetraspanins, is a potent inhibitor of cancer metastasis in numerous malignancies. CD82 is a highly glycosylated protein, howev...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Theranostics
Autori principali: Li, Jun, Xu, Jiawen, Li, Luhan, Ianni, Alessandro, Kumari, Poonam, Liu, Shuo, Sun, Peiqing, Braun, Thomas, Tan, Xiaoyue, Xiang, Rong, Yue, Shijing
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2020
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7255015/
https://ncbi.nlm.nih.gov/pubmed/32483464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.43865
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi