MGAT3-mediated glycosylation of tetraspanin CD82 at asparagine 157 suppresses ovarian cancer metastasis by inhibiting the integrin signaling pathway

Background: Tetraspanins constitute a family of transmembrane spanning proteins that function mainly by organizing the plasma membrane into micro-domains. CD82, a member of tetraspanins, is a potent inhibitor of cancer metastasis in numerous malignancies. CD82 is a highly glycosylated protein, howev...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Li, Jun, Xu, Jiawen, Li, Luhan, Ianni, Alessandro, Kumari, Poonam, Liu, Shuo, Sun, Peiqing, Braun, Thomas, Tan, Xiaoyue, Xiang, Rong, Yue, Shijing
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7255015/
https://ncbi.nlm.nih.gov/pubmed/32483464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.43865
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