Rescuing Dicer expression in inflamed colon tissues alleviates colitis and prevents colitis-associated tumorigenesis

Chronic inflammation is known to promote carcinogenesis; Dicer heterozygous mice are more likely to develop colitis-associated tumors. This study investigates whether Dicer is downregulated in inflamed colon tissues before malignancy occurs and whether increasing Dicer expression in inflamed colon t...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Theranostics
Autori principali: Wu, Xiaoli, Chen, Xiao, Liu, Hui, He, Zhong-Wei, Wang, Zheng, Wei, Lin-Jie, Wang, Wei-Yun, Zhong, Shouhui, He, Qin, Zhang, Zhechao, Ou, Rongying, Gao, Jian, Lei, Youchun, Yang, Wenjun, Song, Guanbin, Jin, Yi, Zhou, Lingli, Xu, Yunsheng, Tang, Kai-Fu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2020
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7254990/
https://ncbi.nlm.nih.gov/pubmed/32483416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.41894
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