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Unique Haploinsufficient Role of the MicroRNA-Processing Molecule Dicer1 in a Murine Colitis-Associated Tumorigenesis Model

A widespread downregulated expression of microRNAs (miRNAs) is commonly observed in human cancers. Similarly, deregulated expression of miRNA-processing pathway components, which results in the reduction of global miRNA expression, may also be associated with tumorigenesis. Here, we show that specif...

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Hlavní autoři: Yoshikawa, Takeshi, Otsuka, Motoyuki, Kishikawa, Takahiro, Takata, Akemi, Ohno, Motoko, Shibata, Chikako, Kang, Young Jun, Yoshida, Haruhiko, Koike, Kazuhiko
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3759383/
https://ncbi.nlm.nih.gov/pubmed/24023722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071969
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