Potent HCV NS3 Protease Inhibition by a Water-Soluble Phyllanthin Congener

[Image: see text] NS3/4A protease of hepatitis C virus (HCV) plays an important role in viral RNA replication. A 1,4-diphenylbutanedicarboxylic acid derivative, namely, phyllanthin, extracted from the leaf of a herbal plant, Phyllanthus amarus, inhibits HCV NS3/4A protease and replication activities...

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Detalhes bibliográficos
Publicado no:ACS Omega
Principais autores: B, Uma Reddy, Tandon, Himani, Pradhan, Manoj K., Adhikesavan, Harikrishnan, Srinivasan, Narayanaswamy, Das, Saumitra, Jayaraman, Narayanaswamy
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7254805/
https://ncbi.nlm.nih.gov/pubmed/32478245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.0c00786
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