Epidermal growth factor upregulates expression of MUC5AC via TMEM16A, in chronic rhinosinusitis with nasal polyps

BACKGROUND: Mucus hypersecretion and goblet cell upregulation are common features of chronic rhinosinusitis with nasal polyps (CRSwNP). Although epidermal growth factor (EGF) has been reported to stimulate the expression of MUC5AC, the major macro-molecular constituent of airway mucus, the precise m...

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Detalhes bibliográficos
Publicado no:Allergy Asthma Clin Immunol
Main Authors: Jiao, Jian, Zhang, Tao, Zhang, Yu, Li, Jingyun, Wang, Min, Wang, Ming, Li, Ying, Wang, Xiangdong, Zhang, Luo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7254766/
https://ncbi.nlm.nih.gov/pubmed/32514271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13223-020-00440-2
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