TMEM16A-Mediated Mucin Secretion in IL-13-Induced Nasal Epithelial Cells From Chronic Rhinosinusitis Patients

PURPOSE: Chronic rhinosinusitis with nasal polyps (CRSwNP), a mainly Th2 cytokine-mediated disease, often involves mucus secretion. Recent evidence suggests that transmembrane protein 16A (TMEM16A), a calcium-activated Cl(-) channel (CaCC), can regulate mucus secretion from airway epithelium by tran...

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Detalhes bibliográficos
Publicado no:Allergy Asthma Immunol Res
Main Authors: Zhang, Yu, Wang, Xiangdong, Wang, Hong, Jiao, Jian, Li, Ying, Fan, Erzhong, Zhang, Luo, Bachert, Claus
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Academy of Asthma, Allergy and Clinical Immunology; The Korean Academy of Pediatric Allergy and Respiratory Disease 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4446635/
https://ncbi.nlm.nih.gov/pubmed/25749771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4168/aair.2015.7.4.367
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