Ciliary Neurotrophic Factor Acts on Distinctive Hypothalamic Arcuate Neurons and Promotes Leptin Entry Into and Action on the Mouse Hypothalamus

In humans and experimental animals, the administration of ciliary neurotrophic factor (CNTF) reduces food intake and body weight. To gain further insights into the mechanism(s) underlying its satiety effect, we: (i) evaluated the CNTF-dependent activation of the Janus kinase 2 (JAK2) and signal tran...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Venema, Wiebe, Severi, Ilenia, Perugini, Jessica, Di Mercurio, Eleonora, Mainardi, Marco, Maffei, Margherita, Cinti, Saverio, Giordano, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Cellular Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7253709/
https://ncbi.nlm.nih.gov/pubmed/32528252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.00140
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